Key result
Bronchoscopy reveals a pulmonary artery filling defect as a malignancy rather than a thromboembolism.
Why the study?
Pulmonary artery filling defects are most commonly thromboembolic, but tumor emboli or tumor thrombus can mimic these findings and pose a serious diagnostic challenge.
Case Report (n=1)
Highlights the importance of considering neoplastic causes (tumor emboli or thrombus) in patients with pulmonary artery filling defects and atypical features for thromboembolism.
Answers are grounded in this paper and cite their sources.
Atypical pulmonary artery defects warrant biopsy to exclude malignancy; leaves open need for prospective diagnostic validation.
Pulmonary artery filling defects are most commonly attributed to thromboembolic disease; however, tumor emboli or tumor thrombus can occasionally mimic such findings, posing a serious diagnostic challenge. This communication describes the case of a 65-year-old male with posttuberculosis lung disease who developed chest pain and persistent hemoptysis. Imaging revealed a right upper lobe mass with a nonenhancing filling defect in the right pulmonary artery. Bronchoscopy and subsequent biopsy from the lesion suggested a malignant lesion. This case highlights the importance of considering neoplastic causes in patients with pulmonary artery filling defects and atypical clinical or imaging features for thromboembolism.
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Singla et al. (2026) conducted a case report in Pulmonary artery filling defect (n=1). Bronchoscopy and biopsy was evaluated on Diagnosis of malignant lesion. A pulmonary artery filling defect in a 65-year-old male was identified as a malignant lesion rather than thromboembolism following bronchoscopy and biopsy.
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