On Glumamycin, a New Antibiotic. II. Isolation and Identification of Amino Acids Constituting Glumamycin

Isoation of the amino acids constituting glumamycin, a new antibiotic, was effected. As a result, α(l), β-methylaspartic acid, besides l-aspartic acid was obtained as an acidic amino acid. In addition to l-valine, glycine, and l-proline, d-pipecolic acid was yielded as a neutral amino acid. Further, α, β-diaminobutyric acid was obtained as a basic amino acid and its structure was established to be α, β-diamino-n-butyric acid. For positive confirmation of the structure the acid was synthesized, and it was found that the N, N-dibenzoyl ethyl ester of the synthetic product and that of the basic amino acid derived from glumamycin were in complete agreement.