Key result
Adding routine preoperative laboratory parameters to clinical characteristics improved the discriminative power for predicting 30-day (0.75 to 0.79) and 3-month (0.75 to 0.78) mortality after AVR.
Why the study?
Does the addition of routine preoperative laboratory parameters to clinical characteristics improve the prediction of 30-day and 3-month mortality in patients undergoing aortic valve replacement?
Population
2,198 patients undergoing aortic valve replacement, including 908 with concomitant CABG, mean age 69+/-11…
Comparison
Addition of routine preoperative laboratory… vs Preoperative clinical characteristics alone and…
Design
Cohort
Follow-up
3 months
Authors
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May refine preoperative risk stratification for AVR; hypothesis-generating and requires prospective validation before practice change.
Cohort (n=2,198)
No
Does the addition of routine preoperative laboratory parameters to clinical characteristics improve the prediction of 30-day and 3-month mortality in patients undergoing aortic valve replacement?
Routine preoperative laboratory parameters improve the discriminative power of risk prediction models for 30-day and 3-month mortality after aortic valve replacement compared to clinical characteristics alone or the logistic EuroScore.
Florath et al. (2006) conducted a cohort in Aortic valve replacement (n=2,198). Routine laboratory parameters vs. Clinical characteristics alone was evaluated on 30-day and 3-month mortality. Adding routine preoperative laboratory parameters to clinical characteristics improved the discriminative power for predicting 30-day (0.75 to 0.79) and 3-month (0.75 to 0.78) mortality after AVR.
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