Key result
Psychological stress links to worse glycemic control in established diabetes but not de novo diabetes.
Why the study?
Does psychological stress cause diabetes de novo or worsen glycaemic control in humans?
Does psychological stress cause diabetes de novo or worsen glycaemic control in humans?
Psychological stress is more likely to unmask asymptomatic diabetes by worsening glycaemia rather than causing diabetes de novo.
Answers are grounded in this paper and cite their sources.
May warrant addressing stress to stabilize glycaemia in established diabetes; leaves open any causal role in de novo onset.
Many patients believe that their diabetes has been caused by stress or an adverse life event. Whereas there is strong evidence that psychological stress is related to a deterioration in glycaemic control in established diabetes, there is much less evidence that psychological stress can cause diabetes in humans de novo. It seems more likely that psychological stress produces a deterioration in glycaemia in the non-symptomatic patient which in turn makes diabetic symptoms and the diagnosis evident. The pathogenic mechanisms which have been suggested to relate psychological stress to diabetes are described and reviewed.
No takes yet. Share an insight, caveat, or question.
J K Wales (1995) conducted a review in Diabetes. Psychological stress was evaluated on Diabetes de novo and glycaemic control. Psychological stress is associated with deterioration in glycaemic control in established diabetes, but there is little evidence that it causes diabetes de novo.
Synapse has enriched 10 related papers. Consider them for comparative context: