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September 10, 2026Scientific ReportsOpen Access

Blind SNR estimation in SEM images using hybrid statistical and CNN features

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Authors

KLKai Liang LewKSKok Swee Sim

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Overview

Computational study demonstrates blind SNR estimation in scanning electron microscopy images, highlighting dataset-dependent model performance.

Key Points

  • To develop a blind signal-to-noise ratio estimation framework for scanning electron microscopy images that operates without clean reference images.
  • Constructed HSCF-KANet by fusing lightweight convolutional neural network features with multi-scale local variance and power spectral density descriptors using a Kolmogorov-Arnold Network regression head.
  • Evaluated the framework on three scanning electron microscopy datasets (EPFL CVLab EM, NFFA-EUROPE, and Biofilm) across synthetic Gaussian noise variances ranging from 0.001 to 0.010.
  • HSCF-KANet achieved a mean absolute error of 0.011 dB on EPFL CVLab EM, 0.049 dB on NFFA-EUROPE, and 0.314 dB on Biofilm.
  • Ablation experiments showed that combining convolutional neural networks with Kolmogorov-Arnold Networks yielded the best root mean squared error on NFFA-EUROPE, whereas pairing them with Random Forest was optimal on Biofilm.
  • Cross-dataset evaluations indicated that incorporating frequency-domain features reduced generalization performance across different image sets.

Cite This Study

Lew et al. (2026) studied this question.

synapsesocial.com/papers/6aa27a2a58559d80afc72dafhttps://doi.org/10.1038/s41598-026-68094-5
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