Case report reveals fatal pulmonary hemorrhage during anticoagulation in pediatric septic pulmonary embolism, highlighting the need for balanced antithrombotic strategies.
A limitation of this report is the absence of coagulation parameters at the time of pulmonary hemorrhage.Although anticoagulation may have led to bleeding risk, the fatal hemorrhage was most likely multifactorial, resulting from the combined effects of severe MRSA infection, septic pulmonary embolism, pulmonary vascular destruction, hyperinflammation, sepsis-associated coagulation abnormalities, and anticoagulant therapy.This case emphasizes the need for further studies to define optimal anticoagulation strategies in pediatric SPE complicated by venous thrombosis.
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Yılmaz et al. (2026) studied this question.
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