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September 10, 2026Journal of Alzheimer s Disease

A Bayesian network meta-analysis of specific exercise modalities for depressive symptoms in mild cognitive impairment

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Authors

LXLe XuLWLingyi WeiRLRuimin Li

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Overview

Network meta-analysis reveals dance exercise alleviates depressive symptoms in mild cognitive impairment, highlighting its therapeutic potential as a targeted non-pharmacological therapy.

Key Points

  • To evaluate and compare the relative efficacy of specific exercise modalities for reducing depressive symptoms in individuals diagnosed with mild cognitive impairment.
  • Systematically searched for randomized controlled trials evaluating exercise modalities targeting depressive symptoms in patients with mild cognitive impairment.
  • Conducted a Bayesian network meta-analysis using standardized mean differences across depression scales and ranked interventions using surface under the cumulative ranking curve (SUCRA) metrics.
  • Included 19 randomized controlled trials evaluating nine distinct exercise modalities.
  • Dance exercise was the only intervention demonstrating statistically significant improvement over control (SMD = -0.51, 95% CrI: -0.84 to -0.16) and held the highest rank probability (SUCRA = 80.71%).
  • Analyses revealed moderate overall heterogeneity alongside local inconsistency in several specific comparisons.

Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/6aa27aca58559d80afc739c3https://doi.org/10.1177/13872877261485578
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