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September 10, 2026Annals of Indian PsychiatryOpen Access

Effectiveness of Cognitive Behavioral Therapy as an Adjunct Treatment for Delusions in Patients with Schizophrenia: A Quasi-experimental Pilot Study

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Authors

PGPooja M. GuptaGHGayatri S. HegdeSPSwapna Aditya Pandurangi

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Overview

Quasi-experimental study demonstrates that adjunct cognitive behavioral therapy reduces delusion severity and distress in schizophrenia, suggesting effective non-pharmacological symptom relief.

Key Points

  • To evaluate the effectiveness of cognitive behavioral therapy for psychosis as an adjunct to treatment-as-usual in reducing delusion-related psychopathology in individuals with schizophrenia.
  • Quasi-experimental pilot study with a control group design conducted at a tertiary mental health center in India.
  • Recruited 20 patients with schizophrenia via purposive sampling and allocated them to adjunct CBTp (8–12 sessions plus treatment-as-usual, n = 10) or treatment-as-usual alone (n = 10).
  • Evaluated outcomes using the Scale for the Assessment of Positive Symptoms and the Psychotic Symptom Rating Scales-Delusion Subscale (PSYRATS-DRS), analyzing changes with Mann–Whitney U and Wilcoxon signed-rank tests.
  • The adjunct CBTp group demonstrated significant pre–post symptom reduction compared to the treatment-as-usual control group.
  • Adjunct CBTp led to significantly greater improvements in delusional preoccupation (P = 0.029, r = 0.49), conviction (P = 0.016, r = 0.54), distress (P = 0.005, r = 0.63), and PSYRATS total score (P = 0.015, r = 0.55), showing large effect sizes across domains.

Cite This Study

Gupta et al. (2026) studied this question.

synapsesocial.com/papers/6aa27bfe58559d80afc757c1https://doi.org/10.4103/aip.aip_139_26
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