What does this research mean for the field?

Early initiation of cysteamine therapy combined with living-donor kidney transplantation yields excellent long-term graft function in children with infantile nephropathic cystinosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe the long-term clinical outcome and management of infantile nephropathic cystinosis treated with early medical therapy and living-donor renal transplantation.

September 10, 2026Indian Journal of NephrologyOpen Access

Successful Kidney Transplant in a Case of Cystinosis in a Young Child: A Case Report

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Authors

VSVijay Sinha SKSunil Kumar UKUrvashi Khan

Discussion

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Overview

Case report demonstrates successful living-donor kidney transplantation in a child with infantile cystinosis, highlighting the benefit of combining early cysteamine therapy with timely surgery.

Key Points

To describe the long-term clinical outcome and management of infantile nephropathic cystinosis treated with early medical therapy and living-donor renal transplantation.
Clinical case evaluation of a 3-year-old child (N=1) diagnosed with cystinosis following presentation with Fanconi syndrome, rickets, and corneal crystal identification.
Treatment protocol included early oral cysteamine, topical ophthalmic cysteamine drops, electrolyte replacement, and subsequent living-donor kidney transplantation from the mother at age 10.
The patient experienced progressive renal decline requiring living-donor kidney transplantation at 10 years of age.
At age 14, following four years of post-transplant follow-up, the patient maintains excellent renal graft function on continued cystine-depleting therapy.

Cite This Study

Sinha et al. (2026) studied this question.

synapsesocial.com/papers/6aa27bfe58559d80afc75872 https://doi.org/10.25259/ijn_33_2026

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September 10, 2026Indian Journal of NephrologyOpen Access

Successful Kidney Transplant in a Case of Cystinosis in a Young Child: A Case Report

View Full Paper

Ask AI

Bookmark

Authors

VSVijay Sinha SKSunil Kumar UKUrvashi Khan

Discussion

Member takes

Overview

Case report demonstrates successful living-donor kidney transplantation in a child with infantile cystinosis, highlighting the benefit of combining early cysteamine therapy with timely surgery.

Key Points

To describe the long-term clinical outcome and management of infantile nephropathic cystinosis treated with early medical therapy and living-donor renal transplantation.
Clinical case evaluation of a 3-year-old child (N=1) diagnosed with cystinosis following presentation with Fanconi syndrome, rickets, and corneal crystal identification.
Treatment protocol included early oral cysteamine, topical ophthalmic cysteamine drops, electrolyte replacement, and subsequent living-donor kidney transplantation from the mother at age 10.
The patient experienced progressive renal decline requiring living-donor kidney transplantation at 10 years of age.
At age 14, following four years of post-transplant follow-up, the patient maintains excellent renal graft function on continued cystine-depleting therapy.

Cite This Study

Sinha et al. (2026) studied this question.

synapsesocial.com/papers/6aa27bfe58559d80afc75872 https://doi.org/10.25259/ijn_33_2026

View Full Paper

Ask AI

Bookmark