What does this research mean for the field?

Current eco-pharmacovigilance frameworks lack adequate coverage of Traditional Chinese Medicine's environmental footprint, necessitating a 'One Health' approach that integrates mechanistic toxicology, climate resilience, and green manufacturing to ensure ecological sustainability. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the environmental footprint of Traditional Chinese Medicine across its product life cycle and propose an integrated eco-pharmacovigilance strategy using a One Health perspective.

September 10, 2026Beni-Suef University Journal of Basic and Applied SciencesOpen Access

Eco-pharmacovigilance in traditional Chinese medicine: a review of mechanisms, challenges, and a call for a “One Health” approach

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To evaluate the environmental footprint of Traditional Chinese Medicine across its product life cycle and propose an integrated eco-pharmacovigilance strategy using a One Health perspective.
Conducted a systematic literature search across PubMed, Web of Science, Scopus, and CNKI for studies published through May 2026.
Applied standardized screening criteria for relevance, methodological quality, and thematic scope, including 62 peer-reviewed publications.
Identified primary environmental contamination pathways, including heavy metal accumulation in medicinal flora and pollutant transport enabled by dissolved organic matter from processing residues.
Highlighted under-investigated ecological risks involving the proliferation of antibiotic resistance genes, endocrine-disrupting herbal compounds, and climate-induced quality alterations.
Outlined an integrated mitigation strategy combining mechanistic toxicology, climate adaptation frameworks, green manufacturing, and cross-border regulatory harmonization.

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Implication

Systematic review reveals complex environmental contamination risks in traditional Chinese medicine supply chains, highlighting the necessity of an integrated One Health regulatory approach.

Cite This Study

Zhong et al. (2026) studied this question.

synapsesocial.com/papers/6aa27c2058559d80afc75bd5 https://doi.org/10.1186/s43088-026-00836-w

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Implication

Systematic review reveals complex environmental contamination risks in traditional Chinese medicine supply chains, highlighting the necessity of an integrated One Health regulatory approach.

Eco-pharmacovigilance in traditional Chinese medicine: a review of mechanisms, challenges, and a call for a “One Health” approach

Key Points

Discussion

Implication

Cite This Study

Eco-pharmacovigilance in traditional Chinese medicine: a review of mechanisms, challenges, and a call for a “One Health” approach

Key Points

Discussion

Implication

Cite This Study

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