Case report demonstrates successful clearance of multidrug-resistant Klebsiella sepsis and meningitis in an extremely preterm infant, highlighting cefiderocol as a potential rescue therapy.
We report the case of an extremely preterm neonate (23 + 4 weeks, 486 g) whose mother had a history of multidrug-resistant infections during pregnancy, and who developed multidrug-resistant Klebsiella sepsis, meningitis and subsequent pneumonia. Cefiderocol was used to successfully treat the infections with no known adverse effects. The neonate was discharged home at 51 + 1 weeks.
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