Pre-Existing Cytokine and NLRP3 Inflammasome Activation and Increased Vascular Permeability in Diabetes: A Possible Fatal Link With Worst COVID-19 Infection Outcomes?

The Role of NLRP3 Inflammasome in COVID-19 and Its ComplicationsIn COVID-19 the immune system may react with an exacerbation of cytokine production known as a "cytokine storm" which leads to hyperinflammation and secondary hemophagocytic lymphohistiocytosis (sHLH) or else Macrophage Activation Syndrome (MAS).This is