Highly Efficient Practical Procedure for the Synthesis of Azine Derivatives Under Solvent-Free Conditions

A general and useful method for the synthesis of azines of aromatic aldehydes and ketones in good yields was elaborated. This reaction is carried out under solvent-free conditions and in the absence of catalyst to afford good yields of the relevant azines. The reaction is also environmentally friendly without the inconvenience of undesired by-products and has advantages over the previously reported methods. Products were characterized by the usual procedures (infrared, 1H NMR, and 13C NMR).