Nitration of inexpensive 1,2,4-trichlorobenzene gave 2,4,5-trichloronitrobenzene (90%) which was treated with KF to form 2,4-difluoro-5-chloronitrobenzene (70%). This was selectively hydrogenated over Pd/C to give 2,4-difluoroaniline (80%). Deamination afforded 1,3-difluorobenzene. The sequence avoids the need for costly 1,3-dichlorobenzene.
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Mason et al. (1994) studied this question.
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