Purpose: To report the postmortem histopathologic features that closely resemble the clinical features of parafoveal telangiectasis. Methods: Light and electron microscopy. Results: Histopathologic features included macular edema; telangiectatic vessels; retinal, subretinal, and superficial retinal neovascularization; retinal pigment epithelial hyperplasia around neovascular aggregates; retinal–choroidal vascular anastomosis; and superficial pigmented cells with lipofuscin. Conclusion: The postmortem histopathologic findings in a 36-year-old woman with Down syndrome and other systemic conditions correlate with features noted in previous reports of presumed parafoveal telangiectasis.
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Eliassi-Rad et al. (1999) studied this question.
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