Effect Of Laparoscopic Sleeve Gastrectomy On Weight Loss And Co-Morbid Factors

This study was undertaken to assess medium-term effects of laparoscopic sleeve gastrectomy on body weight and co-morbid factors like diabetes, hypertension, and thyroid imbalance. Forty-two obese subjects [19 male/23 female; age 23-65 yrs; BMI (Body Mass Index) 45±5 kg/m2] underwent evaluation of anthropometric/clinical parameters and blood sugar, hypertension and thyroid function tests before surgery and 9-15 months after surgery. Mean BMI decreased from 45 to 30 after 9-15 months of surgery (p=0.00001). Remission of diabetes mellitus and hypertension (p-value of 0.00001) occurred in all patients except one. In fact, sleep apnoea and asthma was cured in all 5 patients (p-value of 0.001). Out of the 5 patients with thyroid imbalance, all except one were off medication within 5 months (p=0.001). Our study showed that laparoscopic sleeve gastrectomy is effective in producing a significant and sustained weight loss (p=0.00001) and improving DM, hypertension and other co-morbid factors in obese patients.