Why the study?
Do metabolic risk factors predict coronary heart disease in women?
Population
2873 women
Design
Cohort
Follow-up
over 30 years
Key result
Metabolic risk factors such as impaired glucose tolerance (3-fold increased risk) and postmenopausal status (2- to 3-fold increased risk) strongly predicted incident CHD in women over 30 years.
Authors
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Metabolic risk factors including lipids, impaired glucose tolerance, uric acid, central obesity, and menopause are significant predictors of coronary heart disease in women.
Cohort (n=2,873)
Do metabolic risk factors predict coronary heart disease in women?
Metabolic risk factors including lipids, impaired glucose tolerance, uric acid, central obesity, and menopause are significant predictors of coronary heart disease in women.
William B. Kannel (1987) conducted a cohort in Coronary heart disease (n=2,873). Metabolic risk factors vs. Absence of risk factors was evaluated on initial clinical manifestations of CHD. Metabolic risk factors such as impaired glucose tolerance (3-fold increased risk) and postmenopausal status (2- to 3-fold increased risk) strongly predicted incident CHD in women over 30 years.