Since changes occurring in the nerve cell body and of their experiments, were in no doubt that the space its processes in consequence of trauma or disease between the two layers of this reticular leptoproduce effects which must obviously be of funda-meningeal sheath was freely in communication with mental importance to the functioning of the nervous the general subarachnoid space.Earlier workers system as a whole, the central position in the field (Virchow, 1851 ; Robin, 1859; His, 1865), and of neuropathological research has naturally for indeed some later ones also (Bevan Lewis, 1889; many years been occupied by the neuron.The Bruce and Dawson, 1911) appear to have been focusing of attention on the neuron has had, how-preoccupied with the search for the lymphatics of ever, the unfortunate effect of producing a conse-the brain.Most of these workers failed to appreciate quential disregard of other elements.The neglect that the tissue surrounding the blood vessels was to which the neuroglial elements of the nervous lepto-meningeal in origin and regarded this sheath system were for a long time subject was remedied, simply as the tunica adventitia of the vessel.They at least to some extent, when adequate staining believed that the perivascular spaces were lymphatics methods were developed for the demonstration of related to the tunica adventitia of the blood vessels these structures.The evolution of gold and silver entering the central nervous system.There was, impregnation methods enabled great advances to however, no general agreement as to the exact be made in the understanding of the role played situation of these spaces.Even Virchow (1851) and by the neuroglia in normal and pathological pro-Robin (1859), whose names are conjoined in the cesses.At the present time, although it is well eponymous nomenclature of the perivascular space, Protected by copyright.
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Millen et al. (1954) studied this question.
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