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October 29, 2014Rambam Maimonides Medical JournalOpen Access

VTE Registry: What Can Be Learned from RIETE?

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Key result

RIETE registry provides real-world acute VTE data to develop prognostic scores for bleeding and mortality.

Population

Consecutive patients with acute venous thromboembolism (VTE) enrolled in the RIETE Registry

Design

Review

Authors

ITInna TzoranBBBenjamin BrennerMPManolis Papadakis

Discussion

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Overview

RIETE registry data may inform real-world VTE patterns; leaves open need for randomized confirmation before practice change.

Structured PICO

P
Population
An ongoing, international, prospective registry of consecutive patients with acute venous thromboembolism designed to gather and analyze data on real-world treatment patterns and outcomes.
E
Exposure
Real-world management determined solely by physicians

The RIETE registry provides valuable real-world data on the natural history, treatment patterns, and prognosis of unselected patients with acute VTE.

Limitations

  • Patients are not treated with a standardized anticoagulant regimen, as treatment varies with local practice.
  • The definition of fatal PE requires objective confirmation followed by death within 10 days, potentially underestimating sudden unexplained deaths.
  • Data are observational and hypothesis-generating, lacking external control or external adjudication of events.

Cite This Study

Tzoran et al. (2014) conducted a review in Acute venous thromboembolism (VTE). Real-world management of VTE was evaluated. The RIETE registry provides real-world data on the natural history and outcomes of unselected patients with acute venous thromboembolism, enabling the development of prognostic scores for bleeding and mortality.

synapsesocial.com/papers/6aa2d16f3c35dfb37e20771bhttps://doi.org/10.5041/rmmj.10171
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