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February 1, 1986Journal of the American College of CardiologyOpen Access

Infarct expansion: Pathologic analysis of 204 patients with a single myocardial infarct

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Population

204 patients with a single myocardial infarct, autopsied at The Johns Hopkins Hospital

Design

Cross-sectional

Key result

Larger, more transmural infarcts and those in the left anterior descending artery distribution were associated with significantly greater infarct expansion (p<0.001).

Authors

JPJohn S. PiroloGHGrover M. HutchinsGMGary Moore

Discussion

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Overview

Infarct expansion is associated with larger, transmural infarcts in the LAD distribution, but is less marked in hearts with pre-existing left ventricular hypertrophy.

Study Design

Type

Observational (n=204)

Multicenter

No

Structured PICO

P
Population
204 autopsied patients with a single myocardial infarct evaluated to determine factors associated with infarct expansion.
O
Outcome
Degree of infarct expansionsurrogate

Main Result

p-value: p=<0.001

Infarct expansion is associated with larger, transmural infarcts in the LAD distribution, but is less marked in hearts with pre-existing left ventricular hypertrophy.

Cite This Study

Pirolo et al. (1986) conducted an observational in single myocardial infarct (n=204). Infarct characteristics (size, transmurality, location) was evaluated on Degree of infarct expansion (p=<0.001). Larger, more transmural infarcts and those in the left anterior descending artery distribution were associated with significantly greater infarct expansion (p<0.001).

synapsesocial.com/papers/6aa2d3ae29287ba209a72ed5https://doi.org/10.1016/s0735-1097(86)80504-6
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