House dust mite (HDM) exposure is a strong risk factor for childhood asthma in various parts of the world.1 The 2 predominant species of HDM are Dermatophagoides pteronyssinus (also known as European HDM) and Dermatophagoides farinae (also known as American HDM). In our previous study, the draft genome and transcriptome of D farinae revealed a spectrum of previously unknown allergens.2 In this study, we attempted to sequence a high-quality genome and transcriptome of D pteronyssinus. We further combined genomic and proteomic approaches to uncover previously unrecognized D pteronyssinus allergens as well as identify a number of potential mite allergens on the basis of homology searches of various nonmite sources.
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Liu et al. (2018) studied this question.
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