Key result
Multivessel CABG linked to ~181% higher postoperative AF risk versus single-vessel grafts.
Why the study?
Does multivessel CABG increase the risk of postoperative atrial fibrillation compared to single-vessel CABG in patients with ischemic heart disease?
Cohort (n=431)
Does multivessel CABG increase the risk of postoperative atrial fibrillation compared to single-vessel CABG in patients with ischemic heart disease?
Absolute Event Rate: 18% vs 6.4%
Multivessel CABG is associated with a higher incidence of postoperative atrial fibrillation compared to single-vessel CABG, with left atrial enlargement being the strongest independent predictor.
Multivessel CABG was associated with higher postoperative AF; leaves open whether graft number or LA size should guide prophylaxis.
PURPOSE: To identify prevalence of atrial fibrillation (AF) in dependence of volume of coronary artery bypass grafting (CABG) as assessed by the number of grafts. MATERIAL AND METHODS: The study included 431 patients with ischemic heart disease (IHD) who underwent CABG. Group 1 comprised patients with single-vessel bypass graft (n=47, 78.7% men, mean age 59.6+/-5.6 years), group 2 - with multivessel bypass grafts (n=384, 76.8% men, mean age 61.0+/-8,1 years). During the observation period postoperative AF developed in 3 patients (6.4%) with single vessel bypass graft and 69 patients (18.0%) with multivessel bypass grafts. At multivariate analysis predictive values were significant for the following parameters: aortic cross-clamping time >36 min - 1.7 (95% confidence interval [CI], 1.1-3.2, p=0.03), ischemia time >19 min - 2.0 (95% CI, 1.1-3.7, p=0.02), age >59 years - 2.4 (95% CI, 1.3-4.4, p=0.005), left atrial dimension >39 mm - 3.7 (95% CI, 2.1-6.6, p<0.0001), left ventricular ejection fraction <51% - 1.9 (95% CI, 1.3- 3.3, p=0.04). Predictive value of cardiopulmonary bypass time >56 min 1.2 (95% CI, 0.56-2.8) was not significant (p=0.5). CONCLUSION: In our study AF in the early postoperative period more often occurred in patients who underwent multivessel coronary bypass surgery. The most powerful predictor of AF in these patients was left atrial dimension exceeding 39 mm.
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Рубаненко et al. (2016) conducted a cohort in Ischemic heart disease (n=431). Multivessel bypass grafts vs. Single-vessel bypass graft was evaluated on Postoperative atrial fibrillation. Postoperative atrial fibrillation developed in 18.0% of patients with multivessel bypass grafts compared to 6.4% with single-vessel grafts, with left atrial dimension >39 mm being a strong predictor.
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