Brain Tumor with Extracranial Metastases

Introduction Primary intracranial tumors in general, and primary brain tumors in particular, rarely metastasize outside the cranial cavity. The scarcity of fully documented cases has prompted us to report 2 cases of primary brain tumors which at autopsy were found to have metastasized to extracranial organs. Report of Cases Case 1.—A 40-year-old white man developed signs and symptoms of increased intracranial pressure about 14 months prior to his death. Nine months before death a large portion of a tumor involving the right temporo-occipital area was removed. After the operation his symptoms subsided for a short time. He was referred to Roswell Park Memorial Institute, where 4 months prior to his death during a second craniotomy a partly cystic tumor was removed, along with 90% of the right occipital and part of the parietal and temporal lobes. A small piece of the tumor was immediately autografted into the right thigh. This