Diagnosis of Acute HIV Infection: It's Time To Get Moving!

Editorials2 January 2001Diagnosis of Acute HIV Infection: It's Time To Get Moving!Timothy Flanigan, MD and Karen T. Tashima, MDTimothy Flanigan, MDDrs. Flanigan and Tashima: Brown University School of Medicine; Providence, RI 02906Search for more papers by this author and Karen T. Tashima, MDDrs. Flanigan and Tashima: Brown University School of Medicine; Providence, RI 02906Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-1-200101020-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Despite dramatic advances in the treatment of HIV infection and the resultant decrease in deaths from AIDS, new HIV infections continue to occur among Americans at a relatively steady rate of 40 000 to 45 000 per year (1). More than 90% of cases of acute HIV infection go undiagnosed despite the fact that more than 50% of persons with the disease are symptomatic (2). Although many of these symptomatic patients seek medical attention at emergency departments, urgent care centers, and primary care offices, they often receive the true but highly misleading diagnosis of “viral syndrome” and are told to ...References1. . Update: trends in AIDS incidence—United States, 1996. MMWR Morb Mortal Wkly Rep. 1997;46:861-7. MedlineGoogle Scholar2. Schacker T, Collier AC, Hughes J, Shea T, Corey L. Clinical and epidemiologic features of primary HIV infection. Ann Intern Med. 1996;125:257-64. LinkGoogle Scholar3. Vento S, Di Perri G, Garofano T, Concia E, Bassetti D. Pneumocystis carinii pneumonia during primary HIV-1 infection. Lancet. 1993;342:24-5. CrossrefMedlineGoogle Scholar4. Daar ES, Little S, Pitt J, Santangelo J, Ho P, Harawa N, et al . Diagnosis of primary HIV-1 infection. Ann Intern Med. 2001;134:25-29. LinkGoogle Scholar5. Rich JD, Merriman NA, Mylonakis E, Greenough TC, Flanigan TP, Mady BJ, et al . Misdiagnosis of HIV infection by HIV-1 plasma viral load testing: a case series. Ann Intern Med. 1999;130:37-9. LinkGoogle Scholar6. Kahn JO, Walker BD. Acute human immunodeficiency virus type 1 infection. N Engl J Med. 1998;339:33-9. CrossrefMedlineGoogle Scholar7. Rosenberg ES, Altfeld M, Poon SH, Phillips MN, Wilkes BM, Eldridge RL, et al . Immune control of HIV-1 after early treatment of acute infection. Nature. 2000;407:523-6. CrossrefMedlineGoogle Scholar8. . Prenatal discussion of HIV testing and maternal HIV testing—14 states, 1996-1997. MMWR Morb Mortal Wkly Rep. 1999;48:401-4. MedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Timothy Flanigan, MD; Karen T. Tashima, MDAffiliations: Drs. Flanigan and Tashima: Brown University School of Medicine; Providence, RI 02906Grant Support: In part by the Lifespan/Tufts/Brown Center for AIDS Research (NIH P30-A142853) and AIEDRP (NIH AI 41534).Corresponding Author: Karen T. Tashima, MD, Miriam Hospital/Brown University, 164 Summit Avenue, Providence, RI 02906.Current Author Addresses: Drs. Flanigan and Tashima: Miriam Hospital/Brown University, 164 Summit Avenue, Providence, RI 02906. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDiagnosis of Primary HIV-1 Infection Eric S. Daar , Susan Little , Jacqui Pitt , Joanne Santangelo , Pauline Ho , Nina Harawa , Peter Kerndt , Janis V. Giorgi , Jiexin Bai , Paula Gaut , Douglas D. Richman , Susan Mandel , and Stephen Nichols , for the Los Angeles County Primary HIV Infection Recruitment Network*Diagnosing Primary HIV Infection Eric S. Daar and Susan Little Metrics Cited byHIV/AIDSLaboratory Testing for HIV Infection: Advances After 28 YearsAcute-to-Chronic Ratio as a Metric for HIV SurveillanceStrategies Used in the Detection of Acute/Early HIV Infections. The NIMH Multisite Acute HIV Infection Study: IReductions in HIV transmission risk behaviour following diagnosis of primary HIV infection: a cohort of high-risk men who have sex with menAcute Retroviral SyndromeMeningoencefalitis aguda debida a primoinfección por VIHFrequent detection of acute primary HIV infection in men in MalawiMolecular Diagnostic Techniques and Other Tests for Direct Detection of HIVAcute Human Immunodeficiency Virus Infection in Patients Presenting to an Urban Urgent Care CenterHIV disease in primary careNew methods for the detection of HIVDiagnosing Primary HIV InfectionEric S. Daar, MD and Susan Little, MDLaboratory testing for infection with the human immunodeficiency virus: established and novel approaches 2 January 2001Volume 134, Issue 1Page: 75-77KeywordsAntigensBlood plasmaEmergency departmentHIVHIV infectionsMyalgiaPrimary care physiciansSpecificityViral loadWestern blot ePublished: 2 January 2001 Issue Published: 2 January 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...