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Nucleophilic aromatic substitution of a 2,4-dinitrophenyl substituted pyrazole 1 with primary amines leads to substitution of the pyrazolo substituent. In these nucleophilic aromatic substitution reactions (S N Ar), 5-amino-1 H-4-pyrazolecarbonitrile (3) acts as a new leaving group.
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Bakavoli et al. (2008) studied this question.
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