Key result
Skeletonized radial and gastroepiploic arteries may improve patency but lack evidence to replace pedicled techniques.
Why the study?
Does the use of skeletonized radial and gastroepiploic arteries improve graft patency and clinical outcomes in humans undergoing coronary revascularisation surgery compared to a traditional pedicled technique?
Systematic Review (n=1,523)
Does the use of skeletonized radial and gastroepiploic arteries improve graft patency and clinical outcomes in humans undergoing coronary revascularisation surgery compared to a traditional pedicled technique?
There is currently insufficient high-quality evidence to recommend skeletonization of radial or gastroepiploic conduits over traditional pedicled techniques in CABG.
Does not support routine skeletonization of radial or gastroepiploic conduits in CABG; leaves open the need for larger RCTs to confirm patency gains.
The use of a skeletonized internal thoracic artery in coronary artery bypass graft surgery has been shown to confer certain advantages over a traditional pedicled technique, particularly in certain patient groups. Recent reports indicate that radial and gastroepiploic arteries can also be harvested using a skeletonized technique. The aim of this study is to systematically review the available evidence regarding the use of skeletonized radial and gastroepiploic arteries within coronary artery bypass surgery, focusing specifically on it's effect on conduit length and flow, levels of endothelial damage, graft patency and clinical outcome. Four electronic databases were systematically searched for studies reporting the utilisation of the skeletonization technique within coronary revascularisation surgery in humans. Reference lists of all identified studies were checked for any missing publications. There appears to be some evidence that skeletonization may improve angiographic patency, when compared with pedicled vessels in the short to mid-term. We have found no suggestion of increased complication rates or increased operating time. Skeletonization may increase the length of the conduit, and the number of sequential graft sites, but no clear clinical benefits are apparent. Our study suggests that there is not enough high quality or consistent evidence to currently advocate the application of this technique to radial or gastroepiploic conduits ahead of a traditional pedicled technique.
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Massey et al. (2007) conducted a systematic review in Coronary artery bypass surgery (n=1,523). Skeletonization of radial and gastroepiploic arteries vs. Traditional pedicled technique was evaluated on Angiographic patency, conduit length, and clinical outcomes. Skeletonization of radial and gastroepiploic arteries may improve short- to mid-term angiographic patency and increase conduit length, but lacks sufficient high-quality evidence to advocate routine use over pedicled techniques.
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