The local Shwartzman reaction was elicited in the rabbit oral cavity and skin with endotoxin prepared by phenol-water extraction procedure from a strain of oral Veillonella. Lipid-carbohydrate-protein products prepared by same procedure from viridans streptococci, or a solution of physiologic saline did not produce this reaction in either tissue. Lesions obtained in oral mucosa with each substance were grossly and histologically similar to lesions obtained with the same material in skin.
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Rizzo et al. (1960) studied this question.