The reaction of hexachloroacetone (HCA) with various diamines led either to the corresponding diamides or to cyclic ureas, depending on the molar ratio of the reactants. In the cases of ethylenediamine, 1,2‐diaminocyclohexane and o‐phenylenediamine, the reaction with HCA also formed bisimidazole derivatives. These latter unexpected products were also formed when the diamine reacted with trichloroacetate esters or with carbon dioxide.
No takes yet. Share an insight, caveat, or question.
Rezende et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: