Transmission of a T-Cell Lymphoma by Allogeneic Bone Marrow Transplantation

2][3] These post-transplantation cancers are usually associated with exposure to radiation, other genotoxic agents, or Epstein-Barr virus; in rare cases, they result from the transfer of neoplastic cells in transplanted tissue. 4e describe two sisters, one the donor and the other the recipient of a bone marrow transplant, in whom subcutaneous panniculitic T-cell lymphoma 5,6 developed three years after the procedure.The finding of identical T-cell clones in the tumors of both sisters implicated the transfer of neoplastic T cells during bone marrow transplantation as the cause of the recipient's subcutaneous lymphoma.