Extremely Stable Copper–Polymelamine Composite Material for Amperometric Hydrogen Peroxide Sensing

For the first time, electroactive poly(melamine) film has been prepared and evaluated to function as a matrix to immobilize “spherical” copper nanoclusters and also as a ligand to form a copper complex with enhanced electrocatalytic activity. This is a simple two‐step process that involves first polymerization of melamine on a screen‐printed carbon electrode followed by electrodeposition of copper without using harmful and environmentally toxic chemicals. It is remarkable that this electrode can electrocatalytically reduce H2O2 at approximately −0.2 V versus Ag/AgCl in pH 7 PBS and possesses superior stability in amperometric analysis of H2O2 under the continuous wall‐jet flow of 1 mM of H2O2 for more than 5 h. Most importantly, we have demonstrated that the as‐prepared copper‐poly(melamine)‐modified electrode can solve the setbacks of copper‐based H2O2 sensors reported so far.