Supramolecular micelles with dual temperature and redox responses for multi-controlled drug release

Novel supramolecular micelles with dual temperature and redox responses were self-assembled from the polyrotaxane of poly(ethylene glycol)–SS–poly(2-(N,N-dimethylamino) ethyl methacrylate) with α-cyclodextrin (PRX–SS–PDMAEMA). The unique micelles present a high drug encapsulation efficiency and multi-controlled drug release behaviour.