In vitro and in vivo evaluation of Rapamycin-eluting nanofibers coated on cardia stents

Diagram of the process used to fabricate non-biodegradable metal stents with an outer layer of Rapa-loaded fibrous membrane using the electrospinning process. With the release of Rapa, the stents are expected to inhibit fibroblast proliferation and tissue hyperplasia, therefore treating a benign cardia stricture.