In vivo demonstration of enhanced probiotic effect of co‐immobilized Lactobacillus acidophilus and Bifidobacterium bifidum

The present study was undertaken to evaluate the effectiveness of co‐immobilization as an efficient method for delivering high numbers of viable probiotic cultures to the host for an enhanced probiotic effect, using in vivo mice models. The co‐immobilized culture of Lactobacillus acidophilus and Bifidobacterium bifidum was fed to eight groups of conventional mice. A greater persistence of probiotic cultures was noticed in the intestinal contents of the groups fed on co‐immobilized cells. Further, the supplementation of diet with co‐immobilized culture also resulted in maximum lowering of faecal coliforms and the enzymatic activity as compared to the prestudy level.