In conformity with findings of previous work on indols and in contradistinction to more recent work on pyrrols, the action of diazoesters on indol leads to 3-substituted as well as a small amount of 1:3-disubstituted derivatives. The formation of 2-substituted derivatives could not be demonstrated. The reaction discussed is a convenient one for the synthesis of a wide diversity of indol compounds.
No takes yet. Share an insight, caveat, or question.
Jackson et al. (1935) studied this question.