Key result
Adrenal pheochromocytoma linked to inverted takotsubo syndrome presenting as acute heart failure and pulmonary edema.
Why the study?
Pheochromocytoma is increasingly recognised as a trigger for Takotsubo syndrome, but its pathognomonic symptoms are rarely present and diagnosis is often delayed.
Case Report (n=1)
Pheochromocytoma can rarely present as an inverted takotsubo syndrome complicated by acute heart failure and pulmonary edema.
Consider pheochromocytoma in inverted takotsubo with acute heart failure; extends rare associations but leaves open systematic evaluation.
Takotsubo syndrome is a rare but emerging form of acute reversible myocardial injury characterized by transient systolic LV dysfunction, often related to emotional or physical stress. Pheochromocytoma is increasingly recognised as another possible trigger. Pheochromocytoma is a rare catecholamine-secreting tumour arising from chromaffin cells within the adrenal medulla or extra-adrenal paraganglia. The pathognomonic quartet of paroxysmal hypertension, palpitations, headache, and diaphoresis is rarely present, and diagnosis is often delayed. We describe a 43-year-old formerly healthy patient with an adrenal pheochromocytoma, presenting as an "inverted" takotsubo syndrome complicated with acute heart failure and pulmonary oedema.
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Spapen et al. (2020) conducted a case report in Pheochromocytoma complicated with "inverted" takotsubo syndrome and acute heart failure (n=1). Adrenal pheochromocytoma was evaluated. A 43-year-old patient presented with acute heart failure and pulmonary oedema due to an "inverted" takotsubo syndrome triggered by an adrenal pheochromocytoma.
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