Microwave‐Irradiated and Classical Syntheses of Symmetric Double Schiff Bases of 1,1′‐Bis(4‐aminophenyl)cyclohexane and their Physicochemical Characterization

A series of new symmetric double Schiff bases of 1,1′‐bis(4‐aminophenyl)cyclohexane and substituted aromatic benzaldehyde are synthesized by classical and microwave‐irradiated techniques. The synthesis time is much shorter and yields of the Schiff bases are found to be better with the microwave‐irradiation technique than classical technique. The purity of Schiff bases is checked by TLC. The structures of Schiff bases are supported by FTIR, 1H NMR, and MS techniques. The biological activity of Schiff bases is checked against Gram‐positive and Gram‐negative microbes. Schiff bases showed moderate antibacterial activity but showed moderate to excellent antifungal activity in comparison with chosen standard drugs.