Key result
Cardiac valvular aneurysms in bacterial endocarditis affect the aortic valve more commonly than the mitral valve, and typically involve the anterior cusp of the mitral valve.
Historical review of the pathology and incidence of mitral valve aneurysms in the context of subacute bacterial endocarditis.
Alerts clinicians to aortic predominance in endocarditis-related aneurysms; leaves open validation with modern echocardiography and cohorts.
The commonest form of cardiac valvular aneurysm is the thrombo-aneurysm of Ribbert (1924), which arises by perforation of an ulcer of the valve cusp into a hollow thrombotic mass and by organization undergoes fibrosis of varying degree. Reports of such aneurysms are not infrequent in the early reports of bacterial endocarditis, but aneurysms having well-organized, smooth, fibrous walls are rare; Saphir and Leroy (1945) believe that some of them are true aneurysms resulting from the action of intra-ventricular pressure upon a portion of valve cusp weakened by valvulitis. The aneurysms affect the aortic valve more commonly than the mitral (Pelvet, 1867; Osler, 1908; Horder, 1909; von Arx, 1914; Soulie and Porge, 1937), and involve the anterior (aortic or right) cusp of the mitral valve much more often than the posterior. Habershon in 1855 described a smooth-walled aneurysm, 1P9 cm. in diameter, affecting the aortic cusp of the mitral valve, and Ogle (1858 a and b) described two smaller examples. Of the 23 cardiac valvular aneurysms collected by Pelvet, 9 affected the mitral valve. More recent instances of mitral valvular aneurysms are those of Horder
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Maclean et al. (1957) conducted a review in Aneurysm of the mitral valve in subacute bacterial endocarditis. Cardiac valvular aneurysms in bacterial endocarditis affect the aortic valve more commonly than the mitral valve, and typically involve the anterior cusp of the mitral valve.
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