More general testing of nanoparticles (NP) for properties that are amenable towards biological activity, and thus potentially conducive to nanotoxicity, should be conducted on a broader scale by experimental chemists to help assess the pernicious threat that NP may present to human health or to the environment. For example, evaluation by measuring NP-biomolecule bioaffinity using techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) is advocated, thereby echoing a similar call to computational and theoretical chemists to expand their studies and make at least part of their work, where feasible, relevant to nanotoxicity.
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Karel D. Klika (2013) studied this question.
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