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January 26, 2026American Journal of Geriatric Psychiatry2 citationsOpen Access

Associations Between ACO Enrollment Status and Drug and Nondrug Costs Among Older Adults Newly Diagnosed With ADRD

SJSeyeon JangXQXuanzi QinMWMin Qi Wang

Key Result

ACO enrollment among Medicare beneficiaries with ADRD was associated with significantly lower drug and nondrug payments, with differences up to $3,670 for those with multisystem morbidity.

Study Design

Type

Cohort (n=111,235)

Structured PICO

Does ACO enrollment reduce drug and nondrug payments in Medicare beneficiaries newly diagnosed with ADRD?

P
Population
111,235 fee-for-service Medicare beneficiaries newly diagnosed with ADRD, tracked from 1 year prior to 5 years after diagnosis.
E
Exposure
Accountable care organization (ACO) enrollment
C
Comparator
Non-ACO enrollment
O
Outcome
Annual Part D prescription drug and nondrug payments

ACO enrollment is associated with reduced prescription drug and nondrug payments among Medicare beneficiaries with ADRD, especially those with a high comorbidity burden.

Abstract

OBJECTIVE: Despite the promising role of accountable care organizations (ACOs) in improving care coordination and lowering total costs of care, it is unclear whether ACO enrollment leads to reduced drug costs among individuals with Alzheimer's disease and related dementias (ADRD). This longitudinal cohort study examined the long-term effects of ACO enrollment on drug and nondrug Medicare payments among Medicare beneficiaries with ADRD, focusing on their comorbidity burden. SETTING, PARTICIPANTS, AND MEASUREMENTS: This study tracked annual Part D prescription drug and nondrug payments of 111, 235 fee-for-service Medicare beneficiaries newly diagnosed with ADRD one year prior and five years after the ADRD diagnosis year (2017) by their ACO enrollment and comorbidity burden status. Comorbidity burden was assessed based on the number of comorbidities ADRD patients had, categorized into no multiple chronic conditions (No MCC; 0 or 1), low MCC (2-4), and multisystem morbidity (MM; 5≤) groups. RESULTS: ACO enrollees spent significantly less on both drug and nondrug payments than non-ACO enrollees, with greater payment differences observed among those with higher comorbidity burden. Drug payment differences ranged from 55 to 93 among those with low MCC and 70-119 among those with MM. Nondrug payment differences were the greatest during the diagnosis year, with 1, 666 for those with MCC and 3, 670 for those with MM. CONCLUSIONS: The findings of this study underscore meaningful differences in prescription drug and nondrug payments associated with ACO enrollment among Medicare beneficiaries with ADRD, particularly among those with greater coexisting comorbidity burden.

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Cite This Study

Jang et al. (2026) conducted a cohort in Alzheimer's disease and related dementias (ADRD) (n=111,235). ACO enrollment vs. Non-ACO enrollment was evaluated on Annual Part D prescription drug and nondrug payments. ACO enrollment among Medicare beneficiaries with ADRD was associated with significantly lower drug and nondrug payments, with differences up to $3,670 for those with multisystem morbidity.

synapsesocial.com/papers/6aa3b41c79218316b55549fehttps://doi.org/10.1016/j.jagp.2026.01.014
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