Case report reveals an IGH-BRAF gene fusion in BRAF Val600Glu-negative hairy cell leukemia, highlighting an alternative oncogenic driver.
Somatic BRAF Val600Glu mutations are present in almost all cases of hairy cell leukemia (HCL) [1]. Amongst rare cases of BRAF Val600Glu mutation negative HCL, exon 11 mutations (Asp449Glu and Phe46...
No takes yet. Share an insight, caveat, or question.
Thompson et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: