The number of people with sickle-cell disease in the United States: national and state estimatesThe South, with a sickle-cell population of 47,354 people, comprised 53% of the sickle-cell population.The estimated sickle-cell population of New York (8308 people), was more than three-fourths of that of the entire Western region.The estimated number of people with sickle-cell disease in each state is shown in Supporting Information Table I.The states with the highest estimated number of people with sickle-cell disease were New York with 8308; Florida with 7539; Texas with 6765; California with 6474; and Georgia with 5890.These five states comprised more than 43% of the total sickle-cell population.Supporting Information Table II shows both the absolute and relative percentages of sickle-cell genotypes by age.The increased mortality for HgbSS/HgbSB 0 leads to an alteration in the relative percentages of sickle-
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Corazzelli et al. (2009) studied this question.
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