Key result
Elevated coronary diffuseness score linked to ~100% greater in-hospital composite risk after CABG.
Why the study?
Does an elevated diffuseness score of coronary artery disease increase morbidity and mortality in patients undergoing primary or reoperative CABG?
Population
1,060 patients undergoing primary or reoperative coronary artery bypass grafting between 1997-2004.
Comparison
Elevated diffuseness score of coronary artery… vs Non-elevated diffuseness score (DS ≤ 18)
Design
Cohort
Follow-up
2 years
Authors
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May aid perioperative risk stratification after CABG; extends angiographic predictors but remains hypothesis-generating pending validation.
Cohort (n=1,060)
Does an elevated diffuseness score of coronary artery disease increase morbidity and mortality in patients undergoing primary or reoperative CABG?
Odds Ratio: 2 (95% CI 1.2–3.32)
Absolute Event Rate: 17.8% vs 9.2%
p-value: p=0.008
Diffuse coronary artery disease, quantified by an angiographic score >18, is an independent predictor of increased in-hospital morbidity and mortality following primary and reoperative CABG.
McNeil et al. (2007) conducted a cohort in Coronary artery disease (n=1,060). Elevated diffuseness score (DS > 18) vs. Lower diffuseness score was evaluated on In-hospital composite outcome (mortality, stroke, MI, deep sternal infection, sepsis, IABP insertion, or return to OR) (OR 2.00, 95% CI 1.20-3.32, p=0.008). An elevated coronary diffuseness score (>18) was independently associated with a higher risk of the in-hospital composite outcome after CABG (17.8% vs 9.2%; OR 2.00; 95% CI 1.20-3.32; p=0.008).
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