Key result
An analysis of 336 patients with congenital heart disease was conducted to evaluate factors producing loss of consciousness or convulsions, though results are not reported in the truncated abstract.
Observational (n=336)
Cyanosis severity may associate with syncope or seizures in congenital heart disease; hypothesis-generating and requires prospective confirmation before informing care.
Introduction history of a paroxysmal loss of consciousness or convulsions occurs in approximately 18% of cases of congenital heart disease.1Knowledge of the factors producing these disturbances is based on clinical observations of a few physicians who have had wide experience in dealing with congenital heart disease. White (1937)2stated: The greater the degree of cyanosis, the greater the likelihood of seizures. Abbott3noted: Epileptiform seizures occur in severe cases and seem to be related to the anoxemia present rather than the raised oxygen unsaturation. It seemed worthwhile to discuss in detail, with some documentation, the factual basis for these statements derived from a large number of patients seen with congenital heart disease. Material and Methods We have analyzed the records of 336 patients with congenital heart disease who gave the history of either loss of consciousness or a convulsion; all were patients at the cardiac
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H. Richard Tyler (1958) conducted an observational in Congenital heart disease (n=336). Cyanosis or anoxemia was evaluated. An analysis of 336 patients with congenital heart disease was conducted to evaluate factors producing loss of consciousness or convulsions, though results are not reported in the truncated abstract.
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