Key result
Acute emotional stress linked to Takotsubo-like MI with complete resolution within 30 days.
Case Report (n=3)
Acute emotional stress can trigger tako-tsubo-like transient left ventricular dysfunction mimicking myocardial infarction, which resolves completely within 30 days.
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Clinicians should consider emotional stress in MI with Takotsubo-like features; case reports leave open mechanistic overlap and require prospective validation.
Emotional distress as a trigger for acute myocardial infarction is beginning to gain credibility as it is recognised that traditional risk factors can account for only half of all myocardial infarctions. Here, three cases of myocardial infarction are presented in the setting of an acute emotional stressor, with coronary angiography showing only minimal coronary artery disease. In all cases striking wall motion abnormalities, mimicking a "tako-tsubo", were noted with complete resolution within 30 days. This pattern suggests tako-tsubo-like transient left ventricular dysfunction.
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Kim A. Connelly (2004) conducted a case report in Myocardial infarction / tako-tsubo phenomenon (n=3). Acute emotional stressor was evaluated on Wall motion abnormalities mimicking a tako-tsubo. Acute emotional stress triggered myocardial infarction with striking wall motion abnormalities mimicking a tako-tsubo that completely resolved within 30 days in three cases.
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