Synthesis of lignin model compound containing a β-O-4 linkage

Development of catalysts for efficient conversion of lignin polymer to value-added materials requires appropriately-functionalized lignin model compounds. The predominant structural feature of lignin biopolymer is an extensive network of β-O-4 linkages. Access to large amounts of a model compound containing the β-O-4 linkage is crucial for the valorisation of lignin biopolymer to aromatic raw materials. Starting from commercially available vanillin, synthesis of dilignol model compound, containing a β-O-4 linkage, is accomplished in good overall yield.