Transcutaneous oximetry, laser Doppler flowmetry and ankle brachial systolic pressure indices were used to investigate blood flow to the feet in 26 subjects with diabetes mellitus and peripheral arterial disease. A total of 21 critically ischaemic feet and 15 non-critically ischaemic feet were investigated. Using laser Doppler flowmetry, non-critically ischaemic feet demonstrated a significant increase in maximum blood flow, and percentage increase in flow following local heating (p = 0.038, p = 0.012) in comparison with critically ischaemic feet. These statistically significant differences reflect an increased hyperaemic response in non-critically ischaemic feet.
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Barbara Wall (1997) studied this question.
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