Prognostic significance of indices of platelets aggregation and interleukin-1β in the acute period of ischemic stroke

AIM: To determine the prognostic significance of indices of platelet aggregation (PA) and the level of interleukin IL-1β in the outcome of ischemic stroke (IS). MATERIAL AND METHODS: day of hospitalization) of IS. The level of interleukin IL-1β in blood serum was defined by enzyme immunoassay method. PA was measured by nephelometric method. RESULTS AND CONCLUSION: According to PA indices, a posteriori prognosis of fatal outcome was 10%, but according to IL-1β indices, it was 0.90%. Consequently, the prognostic significance of PA indices with regard to fatal outcome of IS patients in the acute period is higher than that of IL-1b indices. Taking into consideration the expenses of both methods of diagnosis, the authors conclude that with regard to economic availability, PA measurement as a prognostic-diagnostic method is more acceptable in clinical practice.