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This monograph from the department of medicine of Johns Hopkins University is the most comprehensive review available of the symptoms, laboratory features, and treatment of systemic lupus erythematosus. Since the concept of this disease has broadened greatly in the last few years with the widespread use of the diagnostic plasma L. E. cell test, such a review is particularly timely. The authors have attempted to gain as complete a picture as possible of the natural history of this disease by analyzing the case histories of 138 patients with systemic lupus erythematosus and by correlating their findings with those in the medical literature. They have analyzed the effects of treatment on each of the manifestations of the disease. The review was compiled with the hope of bringing to light new avenues of approach to the study of lupus erythematosus; however, it should also serve as an excellent reference manual for the
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A 1955 study studied this question.
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