Why the study?
Whether Bachmann bundle pacing reduces atrial fibrillation incidence compared with interatrial septum pacing and right atrial appendage pacing remains unclear.
Does Bachmann bundle pacing reduce atrial fibrillation incidence compared with interatrial septum pacing and right atrial appendage pacing?
Comparison
BBp vs IASp vs RAAp
Design
Network meta-analysis
Key result
Bachmann bundle pacing significantly lowered any atrial fibrillation incidence compared with interatrial septum pacing (HR 0.41; 95% CI 0.29-0.57; p<0.001) and right atrial appendage pacing.
Authors
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BBp may reduce AF incidence versus IASp or RAAp; extends observational data and supports dedicated RCTs before practice change.
Meta-Analysis (n=2,843)
Does Bachmann bundle pacing reduce atrial fibrillation incidence compared with interatrial septum pacing and right atrial appendage pacing?
Hazard Ratio: 0.41 (95% CI 0.29–0.57)
p-value: p=<0.001
Bachmann bundle pacing significantly reduces the incidence of any and de novo atrial fibrillation compared to interatrial septum and right atrial appendage pacing, supporting its use as a first-line atrial pacing strategy.
Pajareya et al. (2026) conducted a meta-analysis in Atrial fibrillation (n=2,843). Bachmann bundle pacing vs. Interatrial septum pacing and right atrial appendage pacing was evaluated on Any AF incidence (HR 0.41, 95% CI 0.29-0.57, p=<0.001). Bachmann bundle pacing significantly lowered any atrial fibrillation incidence compared with interatrial septum pacing (HR 0.41; 95% CI 0.29-0.57; p<0.001) and right atrial appendage pacing.