Key result
TAAD diagnostic delays stem from ACS-mimicking presentations, lack of clinician awareness, and limited CT access.
Why the study?
Aortic dissection is a life-threatening, time-critical condition that often presents with varied symptoms, leading to a high occurrence of misdiagnosis and treatment delays.
Systematic Review
Diagnostic delays in type A aortic dissection are common due to variable presentations mimicking other conditions and limited access to advanced imaging, highlighting the need for improved awareness and triage protocols.
Answers are grounded in this paper and cite their sources.
Requires heightened vigilance and expedited CT for nonclassic presentations; extends systematic evidence supporting dedicated aortic dissection pathways in emergency care.
BACKGROUND AND AIM OF STUDY: Aortic dissection (AD) remains a life-threatening and time-critical condition. The classical presentation involves sudden onset, sharp "tearing" chest pain radiating to the back. However, it can present with a myriad of symptoms, leading to a high occurrence of misdiagnosis and delay in treatment. METHODS AND RESULTS: A review of the available literature published on AD and diagnostic delays. A systematic review of the literature performed via PubMed and Google scholar using key search terms such as "type A," "aortic dissection," "delay," "misdiagnosis," and synonyms. The Boolean operator used to narrow results specifically to diagnostic elements of AD. A current lack of data collection has impeded the systematic analysis and review of this condition making it difficult to assess reasons for delay. A review of the literature showed a large variation in the presentation of those that have acute AD. Often the presentation mimics other more common conditions such as acute coronary syndrome. Lack of awareness amongst clinicians means that it is often not considered as a differential. Furthermore, the lack of a discriminator for patients being triaged leads to diagnostic delay; this is exacerbated by limited accessibility to diagnostic tests such as CT. CONCLUSION: Based on the current literature, collaborative data collection, regular audit, national guidance, and communication between Royal Colleges will improve awareness, reduce diagnostic delays, and shine greater light on the issue.
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Yadav et al. (2021) conducted a systematic review in Type A aortic dissection. Diagnostic delays and misdiagnosis was evaluated on Reasons for diagnostic delay. Diagnostic delays in type A aortic dissection are driven by atypical presentations mimicking acute coronary syndrome, lack of clinician awareness, and limited access to CT imaging.
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